[ouch]

I just started Synthroid (levothyroxin) and I have already been taking Ultram. My pharmacist and doc said I can take them together but I'm still nervous about it. I also take Imitrex and Vicodin when I get severe migraines, Klonopin if I can't sleep, is it okay to take those with Synthroid too? If I can take any or all of these with Synthroid, should I wait a certain amount of hours before or after them to take the Synthroid? Thanks!

[tikku]

synthroid and pain medicines like ultram dont have any recorded drug interactions.always take synthroid before breakfast in an empty stomach,b'coz food interferes with absorption.anyway dont take synthroid at night as it interferes sleep b'coz it increases metabolism.take pain meds whenever u want.no room to worry. good luck.

[SARAH A]

You shouldn't have any problems taking Synthroid and Ultram together, or Synthroid and any of the other medications you listed. As far as when you should take it, the only suggestion I could find is that you should take Synthroid on an empty stomach. Otherwise, you should be fine.Of course, as with all medications, if you have any concerns or problems the best course is to consult your doctor.

[estrellastar98]

Synthroid will not interact with any of the other meds.Take Synthroid as directed, usually in the morning 30 minutes before breakfast. Do not take antacids or iron supplements within 8 hours of thyroid medication. Do not change brand names and do not stop taking it without consulting your MD. Do not eat excessive amounts of goitrogenic foods (eg, asparagus, cabbage, peas, turnip greens, broccoli, spinach, brussel sprouts, lettuce, soybeans).However, the other medications DO interact with each other.Ultram and Imitrex shouldn't be taken together. It can be serious if you taken both together often."Patient Management The concomitant use of agents that enhance serotonin activity should be undertaken with great caution. Patients should be monitored for the development of serotonin syndrome during such therapy. The manufacturers of some agents have contraindicated the use of certain drugs due to this problem."(FYI Serotonin Syndrome is what Anna Nicole's son died of)----Ultram, Klonopin, and Vicodin should not be taken together. They all depress the CNS and together can depress it too much and cause problems. This is not too serious of an issue but you definitely shouldn't take them all together on a regular basis."Patient Management The concomitant use of two or more drugs that have the potential to depress CNS function (either as a therapeutic intention or a side effect) is often clinically appropriate. However, it is important to recognize that the risk of unwanted effects may increase with such use. Monitor for additive CNS-depressant effects if two or more CNS depressants are concomitantly used."----Make sure you only go to one doctor and one pharmacy. Most pharmacies probably wouldn't tell you about the 2nd drug interaction, but it can be important, especially if breathing becomes difficult or if you drink at all. Good luck!