12-21-2008, 07:22 AM
To respond to your question 20 mg of oxycodone will provide a similar level of analgesic relief as 7.5 mg of hydromorphone.This being said, and despite being prescribed the medications, the responder Marisa&Mike has reported some misinformation which should be corrected. Oxycodone is available in a short duration or a sustained duration dosage form. Dilaudid (hydromorphone) oral preparation is designed to be given every 4 hours so it is a short acting formulation also.These are both Schedule II controlled substances and have similar potential for abuse. The tendency of patients to develop dependence and/or addiction to opiates is individual. While virtually all people given high potency opiates such as oxycodone or hydromorphone will develop some level of physical dependence if given the medication for an extended period, one is not more likely to cause the dependence than the other. However, if a patient is on the sustained release formulation of oxycodone and the short acting hydromorphone the withdrawals from the hydromorphone will be somewhat shorter. As far as addiction, the risk factors for addiction are more individual than those for physical dependence, and many patients can take either of these medications without developing a psychological addiction, while others would become addicted to either.It should also be understood that when a person takes oxycodone the body converts the medication into other substances through metabolism, one of those substances is hydromorphone.